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Image Search Results
Journal: Translational Stroke Research
Article Title: Phosphodiesterase 10A Inhibition Leads to Brain Region-Specific Recovery Based on Stroke Type
doi: 10.1007/s12975-020-00819-8
Figure Lengend Snippet: TAK-063 treatment-mediated alterations in BDNF expression in striatal tissue. BDNF expression levels measured with tissue ELISA showed elevation at 3 weeks post-striatal stroke in striatal tissue, ipsilateral to the infarct. Treatment with TAK-063 resulted in a significant increase in BDNF levels in the stroke + 3.0 mg/kg versus stroke + vehicle group in ipsilateral striatum; P = 0.005, corrected for multiple comparisons (df = 18, t value = 5.982). Error bars represent mean ± SEM for n = 10 per group
Article Snippet: To measure proBDNF, p75NTR, and pTrkB protein levels, the following kits were used: BDNF (mouse) ELISA kit (Abnova), proBDNF Rapid ELISA Kit (Biosensis), Mouse NGF R/TNFRSF16 DuoSet ELISA (R&D Systems), and
Techniques: Expressing, Enzyme-linked Immunosorbent Assay